I am on isotretinoin and my face is peeling. If I drop everything, which 2 basic steps will fix the dryness?

If you're experiencing isotretinoin dry skin and peeling, it's a common side effect as the medication drastically reduces sebum production. To combat this compromised barrier, two non-negotiable steps are a lipid-preserving gentle cleanser and a ceramide-rich moisturiser. However, dermatologists often recommend a strict 3-step clinical baseline: Cleanse, Moisturise, and Protect (SPF 30+).

Step 1: Lipid-Preserving Cleanser

Indian urban centers have hard water with high Total Dissolved Solids (TDS), including calcium and magnesium. When combined with harsh foaming agents, this strips the remaining lipids from isotretinoin-treated skin. Use a sulfate-free, hydrating cleanser for 60 seconds to remove impurities without disrupting the acid mantle.

Step 2: Barrier-Repair Moisturizer

Isotretinoin depletes the skin's natural lipid barrier, leading to severe isotretinoin dry skin. Apply a moisturizer containing Hyaluronic Acid and Ceramides on damp skin. Hyaluronic acid pulls moisture into the epidermis, while ceramides physically replace the missing lipid matrix to halt peeling and repair the barrier.

The Mandatory Daytime Addition: Sunscreen

While cleanser and moisturizer fix dryness, isotretinoin makes Fitzpatrick III-V Indian skin highly photosensitive. With India's UV index frequently hitting 10+, skipping sunscreen leads to rapid Post-Inflammatory Hyperpigmentation (PIH). Apply a broad-spectrum SPF 50 PA++++ sunscreen using the Two-Finger Rule (approx. 1/4 teaspoon) every morning.

Minimalist Isotretinoin Protocol

• AM Routine: Rinse with plain water (skip cleanser if actively peeling) - Apply Ceramide Moisturizer - Apply SPF 50 PA++++. Wait 60-90 seconds between layers to prevent pilling in 70%+ humidity.
• PM Routine: Wash with a gentle cleanser - Apply a thick layer of Ceramide + Hyaluronic Acid moisturizer on damp skin.
• Contraindications: Strictly avoid Salicylic Acid, Glycolic Acid, Retinol, and Vitamin C while on isotretinoin. These actives will exacerbate peeling and trigger severe contact dermatitis on compromised skin.