Mujhe PCOS hai aur meri neck ke aas-paas ki skin achanak black ho gayi hai, is pigmentation ko kaise treat karein?

PCOS patients mein neck aur lips ke aas-paas hone wali localized hyperpigmentation koi sun tan nahi hai; yeh ek clinical condition hai jise Acanthosis Nigricans kehte hain. Dr. Divya Sharma, MBBS, MD Skin confirm karti hain ki high blood insulin levels, jo Polycystic Ovary Syndrome (PCOS) mein common hai, neck par is specific dark, velvety hyperpigmentation ka kaaran bante hain.

Chest region fair rehta hai kyunki Acanthosis Nigricans specifically intertriginous areas (skin folds) ko target karta hai jahan friction zyada hota hai. Elevated insulin skin par insulin-like growth factor receptors se bind hota hai, jisse keratinocytes (skin cells) tezi se multiply hote hain aur ek velvety texture mein thick ho jaate hain. Saath hi, changing hormones—khaaskar excess estrogen aur progesterone—active melanin production ko trigger karte hain, jisse mouth ke aas-paas dark patches ho jaate hain. 4 Indian cities mein 1204 women par ki gayi ek clinical study se pata chala hai ki 80% se zyada population aisi skin color heterogeneity face karti hai, jo aur bhi badh jaati hai kyunki Indian descent ke logon mein naturally higher baseline melanin production hota hai.

Acanthosis Nigricans & Localized Pigmentation ke liye Clinical Protocol

Ise treat karne ke liye, aapko thickened skin texture aur overactive melanin synthesis dono ko targeted actives use karke address karna hoga:

• Step 1: Chemical Exfoliation (PM, 2-3x a week): Neck par 7% Glycolic Acid toner apply karein. Glycolic acid (ek alpha-hydroxy acid) dead, thickened keratinocytes ke beech ke bonds ko break karta hai, jisse velvety layer ko shed karne ke liye cellular turnover accelerate hota hai.
• Step 2: Tyrosinase Inhibition (AM & PM, Daily): Neck aur lips ke aas-paas 10% Niacinamide serum apply karein. Niacinamide enzyme tyrosine hydroxylase ko inhibit karke melanin ki synthesis ko disrupt karta hai, jisse further localized darkening prevent hoti hai.
• Step 3: UV Protection (AM, Daily): Sun exposure hyperpigmentation ko aur kharab karta hai. UV-induced melanin spikes ko prevent karne ke liye daily ek broad-spectrum SPF 30+ sunscreen apply karein jisme zinc oxide ya titanium dioxide jaise physical blockers hon.