A strictly one-sided patch on your right cheek is highly unlikely to be melasma, which typically presents as symmetrical brown-to-gray patches on both sides of the face. Clinical data shows that unilateral (one-sided) pigmentation is almost always Post-Inflammatory Hyperpigmentation (PIH) triggered by localized trauma, such as acne marks or inflammation.
Dr. Shweta Virmani, MD Dermatology confirms that melasma is seen symmetrically on both sides of the face. In Indian demographics with Fitzpatrick skin types III to V, the skin produces more melanin and reacts rapidly to irritation, making PIH extremely common after acne breakouts.
For PIH, Vitamin C is the superior choice. A 10-20% concentration of L-ascorbic acid works by inhibiting tyrosinase, the enzyme responsible for melanin production, effectively fading superficial acne pigmentation within 6 to 8 weeks. Tranexamic acid at 3-5% is better suited for symmetrical melasma, as it blocks the plasminogen pathway to stop UV and hormonal pigment triggers.
Indian skin is highly susceptible to both conditions due to intense UV radiation and visible blue light, which induces persistent pigmentation. A Wood's lamp examination by a dermatologist can clinically confirm if the pigment is epidermal (surface PIH) or dermal (deeper melasma).
Since your right cheek pigmentation is likely PIH, follow this clinical protocol:
- Morning Active: Apply 3-4 drops of a 10% Vitamin C serum for PIH to clean, dry skin to inhibit melanin transfer.
- Protection: Follow immediately with a broad-spectrum SPF 50 sunscreen. UV exposure darkens PIH rapidly; reapplication every 2-3 hours is mandatory in India's hot climate.
- Night Exfoliation: Use a 1-2% salicylic acid cleanser or serum. It stays superficial, keeping PIH risks low while clearing the clogged pores that cause acne pigmentation.
Hinglish version: https://thedermaco.com/blogs/faq/vitamin-c-vs-tranexamic-acid-for-one-sided-cheek-pigmentation-hinglish
